Wednesday, November 26, 2008
10 kinds of drugs so far away from baby asthma
1 glucocorticoid Glucocorticoid is the most effective anti-inflammatory drug. Inhaled corticosteroid is a long-term control of asthma drug of choice they have the advantage of the adoption of smoking, drug direct role in the airway mucosa, the local anti-inflammatory effects of a strong systemic side effects less. But it usually takes a long time, in order to standardize the inhalation from the role of prevention. In the acute asthma attack should be the first inhaled β2 agonist, and then inhaled corticosteroid. For seasonal asthma in children, can be expected to attack from 2 to 4 weeks before the beginning of a sustained, regular inhaled corticosteroid. At present, there are listed drug beclomethasone dipropionate, budesonide and fluticasone propionate 3, in which the body of the last two fewer side effects, and a stronger role. Its form can be divided into 3 categories: quantitative pressure inhalation aerosol, dry-powder inhaler and atomized solution. In addition, there are oral and intravenous administration in two ways. 2 β2 agonist β2 agonist is the most widely used clinical bronchodilation agents, in particular, are widely used in aerosol treatment for acute asthma. Short-acting β2 agonist salbutamol have in common and terbutaline. Inhalation drug delivery, including aerosols, dry powder and atomized solution can be directly on bronchial smooth muscle. Their asthma faster, usually within a few minutes effect, the effect can be maintained 4 to 6 hours to relieve acute symptoms of asthma drug of choice, can also be used as exercise-induced asthma drug prevention. Drug overdose or adverse reactions, including heart palpitations, muscle tremors, cardiac rhythm disorders such as hypokalemia and should be used. Salbutamol each inhaled 100 to 200 micrograms; terbutaline every 250 to 500 micrograms of inhaled, but not a single long-term use. If the amount of 1 day per month or more than 4 times the amount of ≥ 2 aerosol cans to be in use or under the guidance of a doctor to adjust medication. Symptoms of less serious cases may also have oral drug delivery. Application of long-short-acting β2 agonist (including oral and inhalation) could result in decreased drug efficacy, drug recovery after a period of time. Β2 receptor agonists long-acting the role of strong and durable, each medication up to 10 to 12 hours, and glucocorticoid combined to reduce the amount of the latter, with synergy, not resistance, cardiovascular effects Very little. Used to prevent an asthma attack at night, the following types: Salmeterol, or by aerosol drug delivery device agent disc, 30 minutes after inhalation effect, the maintenance of more than 12 hours; Formoterol, may be in the form of aerosol drug delivery, inhalation of 3 to 5 minutes effect, the maintenance of 8 to 12 hours; Procaterol hydrochloride, oral administration of 15 to 30 minutes after the onset, maintenance of 8 to 10 hours; After the oral bambuterol lasting effect, a daily meeting, to take before going to bed. At present, the joint recommendation of inhaled corticosteroid and long-acting β2 agonist treatment of asthma, combined with a concerted anti-inflammatory and anti-asthmatic effect. 3 Theophylline With airway smooth muscle relaxation, excitement and respiratory center, such as the role of respiratory muscle. For the long-term control, the main type of people to assist the absorption of glucocorticoid anti-inflammatory used for the prevention of an asthma attack at night and cough at night. Common side effects are nausea, vomiting and arrhythmias, blood pressure dropped, and so on. 4 anticholinergic drugs Zhichuan role than β2 agonist weak effect is also slower, but not the use of long-term resistance, and less adverse reactions. Often combined with β2 agonist, so that to enhance the role of bronchial dilation and lasting. 5 leukotriene receptor antagonist Leukotriene receptor antagonist is a new class of non-glucocorticoid anti-inflammatory drugs, commonly used for drug montelukast, zaru Principal Secretary, with the regular-inhalable corticosteroid combination therapy in children with asthma can be reduced Corticosteroid dose, and increase the inhaled corticosteroid treatment. The drug is well tolerated, side effects of light, easy to take. 6 mast cell membrane stabilizer Mast cell membrane stabilizer, including disodium cromoglycate, is a non-steroid anti-inflammatory drugs for long-term treatment of mild asthma. Can also act on the prevention of exercise-induced asthma, such as cold air to prevent dry-induced breathing attack. Very few side effects, the use of long-term security. 7-antihistamines Antihistamine drugs, including oral cetirizine, loratadine, ketotifen, and so on, the general type of drug is not recommended for children to use. 8 specific immunotherapy Allergic asthma is caused as a result of the main reasons, can not avoid contact with allergens or ineffective treatment, can be considered for the specific allergen immunotherapy. Pollen or dust mite allergy will be able to adopt corresponding allergen extracts for desensitization therapy to alleviate an asthma attack. 9 immunomodulator As a result of recurrent respiratory tract infection induced asthma can be made, as appropriate, the authors added. 10 Chinese Although the emergency treatment of the role of traditional Chinese medicine is not obvious, but sometimes it can be used as auxiliary treatment or prevention. Mitigation and control of asthma, many different types of drugs, application of specific principles should be experienced doctors to decide. In the doctor under the guidance of maintenance therapy at home. If the parents in their own experience, so that the child's condition can not be brought under control, children should go to the hospital for regular treatment. TIPS Do you know what form it drugs? Formulations of drugs that drug applications. Now commonly used drug formulations include: oral, mouth tablets, inhalation, intramuscular injection, intravenous injection, rectal suppository, and so on skin preparations for external use. Although a drug's mechanism of the same. However, different formulations made, use has been limited. For example: Rectal administration of oral drugs can not be; skin drugs for external use can not by oral medication; only intramuscular injection of the drug by intravenous administration can not. Therefore, parents of children in the choice of drugs, we should pay attention to the type of drug, dosage, usage, but also pay attention to the drug dosage form.
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