Tuesday, November 25, 2008

opium+ Alcohol = deadly

Health Canada recently issued a warning: with Alcohol sustained-release opioid analgesics possible joint use of deadly interaction. The warning came after the company PurduePharma prompted its PalladoneXL sustained-release opioid drugs and alcohol use may cause serious and potentially fatal reaction issued. PalladoneXL contains a capsule of hydrogen known as one of sustained-release morphine component, and alcohol use at the same time, the hydrogen-morphine may be rapidly released into the blood and reach dangerous levels, the effect known as dose dumping (dosedumping). For this reason, on July 13 this year, the U.S. Food and Drug Administration (FDA) requested Pur Juan duePharma will PalladoneXL from the United States withdraw from the market. Canadian Ministry of Health said in a warning that the security issue may be limited to Pal Juan ladoneXL a drug, but patients using other slow-release opioid products should also be aware that there may be the same risk. In addition to the use of alcohol, including drinking beer, wine or other distilled liquor, but also including the use of alcohol or prescription drugs for prescription drugs. If you want to know their patients taking drugs of alcohol may be linked with the pharmacist. Sales in Canada, the other sustained-release opioid analgesics are hydrogen-morphine sulfate and morphine in 10 cultivars. In addition to determining PalladoneXL other sustained-release opioid drugs can effect this, the Ministry of Health Canada is asking manufacturers of these drugs to provide their products and the interaction of alcohol-related data. If the factory can not provide data, will be asked to conduct some research work and research requirements within six months to complete. Health Canada will be held within 3 months of submission of data evaluation, if necessary, will take further measures. Upon completion of the assessment, the Ministry of Health request to increase security for the time being written into the prescription drug issue specification, draw up the final results of the study. Canada is currently no drug market PalladoneXL in sales. In Canada there is no PalladoneXL of adverse reactions reported.

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