Tuesday, November 25, 2008

Amebic liver disease affected the brain more

Amoebiasis brain pathology of brain hemorrhage was found in brain tissue necrosis, involving the olfactory tract and bulb, olfactory nerve inflammation, and even necrosis, brain stem belly side of the hypothalamus is also involved. See inside the gray matter necrotizing arteritis, and multiple small abscess, and may find the typical "bovine" amoeba nucleus. Amoebiasis by the amoebic parasite-borne diseases. Parasitic in the human colon in the melting histolytica wall protozoon sometimes invasive enteropathy caused by amoeba. Trophozoites in the wall by the blood or directly to the spread of parenteral organizations, most often involved the formation of liver abscess of liver, other organs such as lung, pleura, the pericardium, brain, peritoneal, genito-urinary system and skin may also be involved. Parasite into the brain when it is caused by brain abscess. In addition to melting protozoon histolytica, but also found in some of the natural world to live in freedom can also be caused by primary amoebic meningoencephalitis. 1, dissolved the organization of the brain abscess amebic rare disease, accounting for parenteral amoebiasis of 3%. From the intestinal parasite, liver, lung lesions, etc. disseminated by the blood flow to the brain to form a brain abscess. If the mother has intestinal amoeba cysts may be infected newborns and infants. After infection and bleeding in the brain appeared to soften purulent lesions, abscesses are usually single, barely weeks away from the formation of fibrous tissue of the wall, the lesions can be found in trophozoites. For the acute onset of clinical manifestations, the rapid progress of the disease, fever, headache, vomiting, disturbance of consciousness, convulsions, coma, may be positioning signs, hemiplegia, aphasia, and so on. Often within a few days in a sharp deterioration in the condition of death. 2, primary amoebic meningoencephalitis (primary amoebic meningo-Encephalitis PAME) Fowler and Corter in 1965, the first report of the human disease, since 1981 all over the world to have more than 130 cases. The disease, although rare, but serious condition. Pathogens is the freedom of living outside the amoeba parasite, a type of amoeba parasite Nyquist (Harmannella) of 2 ameba caused by pest species and Fowleri and austmliensis Harrington (Harmannella) and the amoeba spine Ami Pakistan is the Acanth-amoeba. Naegleria-Fowleri amoeba is one of the most common disease caused by species. The disease mostly children, the incidence of multi-season festival in the summer and fall, Naegleria-Fowler freedom to live in water, moist soil, sewage and other decaying organic matter, or swimming through the nose or infected children washed in warm muddy ditch play Infected water. Amoeba from the nasal mucosa by the plate along the olfactory nerve into the brain. Pathological examination revealed brain hemorrhage in brain tissue necrosis, involving the olfactory tract and bulb, olfactory nerve inflammation, and even necrosis, brain stem belly side of the hypothalamus is also involved. See inside the gray matter necrotizing arteritis, and multiple small abscess, and may find the typical "bovine" amoeba nucleus. The incubation period of 5 to 8 days, acute onset, headache, vomiting, sore, runny nose, the disease after 2 to 3 increase the headache, high fever, vomiting, positive meningeal irritation, and cranial nerve damage, convulsions, coma, the majority of children in the After the patient died about a week. Cerebrospinal fluid white blood increased by neutrophils mainly higher, with red blood cells, increasing protein, reduced sugar, low chloride, the bacteria can not find, at room temperature in the fresh can be found in the cerebrospinal fluid of the activities of the amoeba, or be able to Train amoeba Naegleria-Fowleri. Harmannella meningoencephalitis caused by the pathogenesis is not clear. Acanthamoeba caused by amoebiasis found in ill health or immune deficiencies, in some cases this can be caused by protozoa of primary meningoencephalitis, but the majority of cases of infection in the brain before the head or eye injury history or other factors, Changes in the primary site of the skin, eyes, lungs, stomach and ear, etc.. Brain infection caused by acute inflammation and granuloma, the disease can be found in amoeba, Martinez called granulomatous amoebic encephalitis. Slow onset of the disease, the disease could take more than a few months to 2 to 3 years, cases of child mortality. Diagnosis to be asked in detail about the history of collecting fresh in the cerebrospinal fluid temperatures to find suitable training and amoebic parasite, the parasite is to find the most reliable basis for the diagnosis.

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