Monday, November 24, 2008

Biotechnology for cancer

Biological treatment of tumor-to-date technology: First, genetically modified tumor therapy works. 1 gene-modified vaccine to treat cancer; 2MIK tumor biological treatment technology. Second, DC vaccine. 1. Peptide known to the impact of DC; 2. Tumor antigen-wide impact of DC; 3. Gene transfer to build DC vaccine. Third, CIK in vitro proliferation and transfusion. Other bio-medical research and development of new technologies and application. What is a gene-modified vaccine gene-modified vaccine using modern genetic engineering techniques of autologous or allogeneic to the tumor cells made from genetically modified vaccine. It can stimulate the body produce for patients with tumor-specific immune response to the initiative, which play a role in the anti-tumor. Clinical research has shown that foreign coverage of the vaccine could reduce tumor recurrence and metastasis rate, to extend the survival time for other conventional treatment in patients with ineffective treatment can still receive better results. Why gene-modified vaccine has anti-cancer effect of how the immune system to wake the sleeping to play a role in cancer? Modern oncology and immunology research shows that dendritic cells are the body's most powerful antigen-presenting cells, and GM-CSF (granulocyte - macrophage colony-stimulating factor) is a dendritic cell development, and the role of chemokines The essential cytokines. Using radiation to eliminate the carcinogenic potential of GM-CSF gene-modified vaccine was injected in the skin of patients can continue to secrete GM-CSF factor in local produce high concentrations of GM-CSF, and chemokine-induced dendritic cell aggregation . Debris vaccine uptake by dendritic cells and processed as a tumor antigen presented to lymphocytes and activated T lymphocytes, and specifically anti-tumor cells. Is the vaccine can induce anti-tumor-specific immune initiative of the new treatment.

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