Diuretics are "double-edged sword"

Wang Mother suffering from long-term high blood pressure, had been taking blood pressure medicine horizon film category, the results have been very good. However, since last October, Wang Mother taking blood pressure medicine horizon film category ineffective, and has high blood pressure, she did not when one thing led to the outcome of cerebral infarction. After careful hospital treatment, Mother Wang finally returned to health. During treatment, in order to lower blood pressure, in addition to the hospital to take Mother Wang nifedipine sustained-release tablet formulations, she returned to take a piece of clonidine and Hydrochlorothiazide, has been satisfied with the results of the blood pressure effects. Clonidine tablets and Hydrochlorothiazide cheap, has a certain effect, the number of elderly patients are often used as a blood pressure drug of choice. However, the simple use of clonidine blood pressure tablets, a long time, the effect would be weakened. As a result, clonidine piece suit with the needs and diuretics can synergy play. And Hydrochlorothiazide is a diuretic effect and in step-down, said the step-down of diuretic drugs. Wang Mother take every day as a result of these two drugs, the normal blood pressure. However, after some time, Wang Mother often feel chest tightness, a little gas does not take on the feeling. Check to go to the hospital and found elevated triglycerides in the blood, also have abnormal electrocardiogram. Zhang Zhuren medical center asked the King Mother medication and they think that the king have a Mother cause of this phenomenon is that long-term use Hydrochlorothiazide. Zhang Zhuren said that application of the treatment of diuretics to alleviate the burden of heart because of diuretics by increasing Painiao Liang, so that the body of blood volume reduction from the venous blood to the heart, so that the heart of the work to alleviate the burden to the treatment of effort Failure. However, clinical found that the diuretic is a double-edged sword. It helps in the treatment of coronary heart disease, high blood pressure can lead to long-term use in patients with coronary heart disease. If the long-term oral Hydrochlorothiazide, which can cause acid-base disturbance in the blood, resulting in cardiac hypertrophy, the increase in oxygen consumption, induced by coronary heart disease, also found that long-term Hydrochlorothiazide, can be induced by high blood fat, low - High density lipoprotein, high density lipoprotein level, which will promote the hardening of the arteries, induced by coronary heart disease. In addition, the use of thiazide-type drugs can help alleviate Shuinazhuliu, but the long-term use of such drugs can cause a variety of metabolism, such as hypokalemia, hyperglycemia, high uric acid, lipid metabolism, and so on. Thiazide diuretics used alone or combined for mild to moderate high blood pressure treatment, some patients have a significant effect, cost-effective and, therefore, some of the retirement of relatively weak economic strength of the elderly, like the use of This low-cost diuretics economic treatment of high blood pressure medicine. However, the elderly due to the lack of basic medical knowledge, often ignored the adverse drug reaction, leading to adverse consequences. As a result, use of thiazide diuretics category, in need of doctors under the guidance of the application to pay close attention to changes in metabolism, to avoid the possible adverse reactions.