Britain found important clues to the origin of AIDS

National Institute for Medical Research in London on the 10th announced by the scientists found that a very important clues AIDS --- as long as the change Trim5α human genes generated by an amino acid protein, HIV can be transmitted from them. Scientists believe the discovery of human understanding of the origin of AIDS is very important to the research-based, gene therapy can be used to develop new means of treatment of AIDS. Since the AIDS virus in laboratory experiments, it is difficult to spread monkey cells, scientists believe that this shows that animal cells and human cells, there are some significant differences, resulting in animal cells from HIV infection. After comparing the human genome and the rhesus monkey genes, the researchers found that rhesus monkeys known as a Trim5α the Trim5α of human genes and proteins produced by genes in a different amino acid, which led to important changes in the rhesus monkey protein can prevent HIV replication. Monkey with an alternative source of protein of human protein found that human cells have the capacity to suppression of the AIDS virus. Even more exciting is that the researcher found that only a change in the human protein amino acid can reduce the vulnerability of cells. London's National Institute for Medical Research scientists believe that if humanity has a rhesus monkey with the same gene Trim5α, HIV will not be able to cause harm to human. The study found that the origin of AIDS provides a new perspective, but also a means of gene therapy to provide unprecedented new ways. The researchers believe that based on the discovery, in theory, the use of gene therapy for the treatment of AIDS is feasible. The researchers envisage, first of all, extract the white AIDS patients, white blood cell cloning and gene-modified, and then the individual to individual into the way that these cells will prevent the AIDS virus in patients with further attacks, so that the transmission of AIDS patients have a certain Immunity. Gene therapy is the genetic material into human cells to treat human diseases as a technical experiment. The technology has been used in the treatment of Parkinson's disease, cystic fibrosis and cancer. But the cure in two patients immune deficiency of France after the boy and found that the treatment would lead to leukemia. National Institute for Medical Research in London virology head Jonathan stressed that while the study is very important, but from the actual clinical application is still a long period of time, be adopted by a large number of animal tests and clinical trials.